Fecal Microbiota Transplantation for IBS (NCT05776914)
Efficacy and Safety of Proteolytic Activity-Guided Fecal Microbiota Transplantation for Irritable Bowel Syndrome (PRAGMAT Trial)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to learn the efficacy and safety of fecal microbiota transplantation (FMT) using stool from a donor with low proteolytic activity and containing the bacteria Alistipes putredinis in patients with irritable bowel syndrome (IBS) and high proteolytic activity. Proteolytic activity is the breakdown of proteins into smaller polypeptides or amino acids.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic in Minnesota — Rochester, Minnesota
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Mayo Clinic in Minnesota — Rochester, Minnesota
📞 Contact the Study Coordinator
Phone: (507) 538-7774
Email: pedelty.jonah@mayo.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Irritable Bowel Syndrome
- Assessment of Psilocybin (TRP-8802) in Concert With Psychotherapy in Patients With Irritable Bowel Syndrome (IBS) — Boston, Massachusetts
- Pilot Study of the Physiological Effects of an Integrative Medicine Approach in Irritable Bowel Syndrome — Philadelphia, Pennsylvania
- A Well-Being Intervention for People With IBS — Madison, Wisconsin
- Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome — Camden, New Jersey
- Defining Objective Markers of Compliance for Dietary Therapies in IBS — Ann Arbor, Michigan
- Mucosal and Microbiota Changes During Acute Campylobacteriosis — Rochester, Minnesota
Explore by condition: All Irritable Bowel Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.