Validation of a Molecular Test for Risk-stratification of Patients With High-risk Intestinal Metaplasia (GCEP2 Study) (NCT05782465)
🩺 Plain-English Summary (8th-Grade Level)
This study is carried out to find out if a customized molecular test can identify a subgroup of patients with very-high-risk of developing stomach cancer within patients with intestinal metaplasia (IM). The investigators hypothesise that the incidence of dysplasia and GC cases in the molecular-test-positive group will be significantly higher than that in the molecular-test-negative group. Such a test has the potential to guide clinicians to better manage patients with IM by allowing endoscopic surveillance to be focused on individuals at very-high-risk of developing stomach cancer, at the same time avoiding or reducing endoscopies for those at lower risk.
Who can join: Review the eligibility criteria below.
Location: Stanford University — Stanford, California
Age range: 50 Years to 75 Years
🧪 Interventions in This Study
- Blood Collection, processing and analyses (PROCEDURE)
- Gastroscopy and biopsies collection (PROCEDURE)
- Urea Breath Test (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- Stanford University — Stanford, California
- The Chinese University of Hong Kong — Hong Kong,
- Nihon University School of Medicine — Tokyo,
- National University Hospital — Singapore,
- Singapore General Hospital — Singapore,
- Tan Tock Seng Hospital, Singapore — Singapore,
- Yonsei University, Republic of Korea — Seoul,
- National Taiwan University Hospital — Taipei,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Stomach Neoplasm clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.