🏛️ Verified NIH Record • Updated 2026-07-09
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty) (NCT05787821)
Persona® OsseoTi® Keel Compatibility Study-A Multicenter Cohort Study A Prospective, Post-market Clinical Follow-up Study to Demonstrate Safety, Performance and Clinical Benefits of the Persona Knee System Portfolio and Its Instrumentation
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Zimmer Biomet
🩺 Plain-English Summary (8th-Grade Level)
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Who can join: Review the eligibility criteria below.
Location: Denver Hip & Knee, Inc. — Parker, Colorado
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- Denver Hip & Knee, Inc. — Parker, Colorado
- Foundation for Orthopaedic Research & Education — Tampa, Florida
- Northside Hospital, Inc. — Atlanta, Georgia
- U of L Health — Louisville, Kentucky
- University of Michigan — Ann Arbor, Michigan
- Mayo Clinic — Rochester, Minnesota
- Mississippi Sports Medicine and Orthopaedic Center — Jackson, Mississippi
- New Mexico Orthopaedic Associates — Albuquerque, New Mexico
- Syracuse Orthopaedic Specialists — DeWitt, New York
- NYU — New York, New York
- St. Francis Hospital & Heart Center — Roslyn, New York
- OrthoCarolina Research Institute, Inc. — Charlotte, North Carolina
- Duke University — Morrisville, North Carolina
- Cleveland Clinic — Cleveland, Ohio
- UT Health at Houston — Houston, Texas
- UVA Health Orthopedic Center — Charlottesville, Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Knee Pain Chronic
- Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty — Jacksonville, Florida
- Cemented vs Cementless Persona Keel RCT — Westminster, Colorado
- Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain — Chicago, Illinois
- Persona Total Knee Arthroplasty Outcomes Study — Denver, Colorado
- Persona Ti-Nidium Post-Market Clinical Follow-up — Parker, Colorado
Explore by condition: All Knee Pain Chronic clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.