๐๏ธ Verified NIH Record โข Updated 2025-06-10
Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study (NCT05797896)
A Multicentre, Natural History, Non-interventional Study Evaluating Biomarkers In Participants With Geographic Atrophy(GA) Secondary To Age-Related Macular Degeneration (AMD)
๐ต Active, Not Recruiting Interventional Protocol ๐ Observational Clinical Research Sponsor: Complement Therapeutics
๐ฉบ Plain-English Summary (8th-Grade Level)
An observational study to investigate the natural history and evaluate biomarkers of participants with geographic atrophy secondary to age-related macular degeneration
Who can join: Review the eligibility criteria below.
Location: Global Research Management โ Glendale, California
Age range: 65 Years
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (22 Sites)
- Global Research Management โ Glendale, California
- Northern California Retina Vitreous Associates โ Mountain View, California
- Midwest Eye Institute โ Carmel, Indiana
- Mid Atlantic Retina Specialists โ Hagerstown, Maryland
- Sierra Eye Associates โ Reno, Nevada
- Verum Research LLC โ Eugene, Oregon
- Mid Atlantic Retina โ Philadelphia, Pennsylvania
- Retina Research Institute of Texas โ Abilene, Texas
- Texas Retina Associates โ Plano, Texas
- San Antonio Eye Center โ San Antonio, Texas
- Belfast City Hospital โ Belfast,
- Bradford Royal Infirmary โ Bradford,
- Frimley Park Hospital โ Frimley,
- Gloucestershire Royal Hospital โ Gloucester,
- Liverpool Hospital โ Liverpool,
- Moorfields Eye Hospital โ London,
- Western Eye Hospital โ London,
- Manchester Royal Eye Hospital โ Manchester,
- Newcastle Hospital โ Newcastle,
- Nottingham City Hospital โ Nottingham,
- University Hospital Southampton โ Southampton,
- Sunderland Eye Infirmary โ Sunderland,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Dry Age-related Macular Degeneration
- Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE III) โ Beverly Hills, California
- Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD) โ Beverly Hills, California
- Phase 3 Study to Assess Efficacy, Safety & Tolerability of OCU410 For Geographic Atrophy Secondary to Dry AMD โ Phoenix, Arizona
- A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy) โ Beverly Hills, California
- Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration โ Baltimore, Maryland
Explore by condition: All Dry Age-related Macular Degeneration clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.