The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization (NCT05814705)
Comparison of High-protein Formulation With/Without Urolithin a During a Unilateral Knee Immobilization: a Pilot Proof-of-concept Trial
🩺 Plain-English Summary (8th-Grade Level)
There are times in life when people cannot use their muscles, such as during illness or injury. Muscle and mitochondria (the 'energy factory' in cells) health decline very quickly when people cannot use their muscles, but certain foods can help reduce these declines. Recent research suggests that Urolithin A, which is a natural compound that can be produced after eating pomegranates, nuts, and berries, improves muscle health. In this study, the investigators aim to investigate if a protein beverage (standard care during disuse) with or without Urolithin A can reduce or prevent the loss of muscle health while wearing a knee brace (muscle disuse).
Who can join: Review the eligibility criteria below.
Location: McMaster University — Hamilton, Ontario
Age range: 18 Years to 30 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- McMaster University — Hamilton, Ontario
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Healthy
- Xanthohumol Metabolism and Signature — Portland, Oregon
- Examining the Effects of Regular Brief Internet-based Meditation Practice on Mental Health and Well Being — Stanford, California
- A Provider Intervention to Reduce Financial Toxicity in Patients With Cancer Through Improved Treatment Cost Discussions — Detroit, Michigan
- A Trial to Evaluate Tolerability and Immunogenicity of V540D in Healthy Adults (V540D-004) — Hollywood, Florida
- Pediatric Parenting Support in Flint — Flint, Michigan
- Biomarker-estimated Flavanol Intake in Davis (FID) — Davis, California
Explore by condition: All Healthy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.