🏛️ Verified NIH Record • Updated 2026-06-18

The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY) (NCT05820087)

The HistoSonics Edison System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY US)

🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: HistoSonics, Inc.

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this trial is to evaluate the effectiveness and safety of the HistoSonics Edison System for the destruction of kidney tissue by treating primary solid renal tumors.

Who can join: Review the eligibility criteria below.

Location: University of Southern California — Los Angeles, California

Age range: 22 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (15 Sites)

  • University of Southern California — Los Angeles, California
  • University of California, Los Angeles (UCLA) — Los Angeles, California
  • Providence Mission Hosptial — Mission Viejo, California
  • Yale School of Medicine — New Haven, Connecticut
  • AdventHealth Celebration — Celebration, Florida
  • Johns Hopkins University — Baltimore, Maryland
  • Massachusetts General Hospital — Boston, Massachusetts
  • Northwell Health — Lake Success, New York
  • NYU Langone Health — New York, New York
  • Icahn School of Medicine Mount Sinai — New York, New York
  • University of Rochester Medical Center — Rochester, New York
  • The Ohio State University Comprehensive Cancer Center — Columbus, Ohio
  • UT Southwestern Medical Center — Dallas, Texas
  • Swedish Medical Center — Seattle, Washington
  • University of Wisconsin School of Medicine and Public Health — Madison, Wisconsin

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Renal Cancer clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗