Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults (NCT05830942)
Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
🩺 Plain-English Summary (8th-Grade Level)
Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging) aerobic walking exercise with non-invasive electrical brain stimulation may be effective at restoring lost function. This study tests whether electrical stimulation of prefrontal brain regions is more beneficial than sham stimulation.
Who can join: Review the eligibility criteria below.
Location: University of Florida — Gainesville, Florida
Age range: 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- University of Florida — Gainesville, Florida
- Brooks Rehabilitation — Jacksonville, Florida
📞 Contact the Study Coordinator
Phone: (352) 376-1611
Email: davidclark@ufl.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cognitive Dysfunction
- PREsurgical Cognitive Evaluation Via Digital clockfacEdrawing — Gainesville, Florida
- Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment — Los Angeles, California
- Fareon Open Label Device Clinical Trial — New York, New York
- A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7) — Chandler, Arizona
- Stem Cell Therapy for Early Alzheimer's Disease — Houston, Texas
- ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults — New Brunswick, New Jersey
Explore by condition: All Cognitive Dysfunction clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.