END - VT Cohort Study (NCT05835791)
Prospective Cohort for the sEcoNDary Prevention of Ventricular Tachycardia in Patients With Cardiomyopathies (END-VT) Study
🩺 Plain-English Summary (8th-Grade Level)
Ventricular tachycardia (VT) is a life-threatening cardiac rhythm disturbance which leads to sudden cardiac death (SCD), ventricular fibrillation, electrical storm, hemodynamic collapse, and syncope. VT patients with cardiomyopathy (diseased/scarred cardiac muscle) have the highest risk of SCD (\<1-4%) and recurrent VTs (15-35%). Although an implantable cardiac defibrillator (ICD) is the most effective treatment option to prevent SCD, it does not eliminate it. Without VT prevention, recurrent VT and ICD shocks may increase the risk of heart failure and death. The primary objective is to determine the optimal treatment strategy to maximize event-free survival among cardiomyopathy patients with ventricular tachycardia (VT) by the creation of a prospective, multicenter, longitudinal cohort. Also, the investigators will evaluate the epidemiology of VT, adherence to guidelines, safety, effectiveness, and cost-effectiveness of current treatment options for secondary prevention of VT in the real-world Canadian VT population.
Who can join: Review the eligibility criteria below.
Location: Providence Health Care Society — Vancouver, British Columbia
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- Providence Health Care Society — Vancouver, British Columbia
- QEII Health Science Centre — Halifax, Nova Scotia
- Montreal Heart Institute, — Montreal, Quebec
📞 Contact the Study Coordinator
Phone: (902) 473-4272
Email: john.sapp@nshealth.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ventricular Tachycardia
- Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) — Chandler, Arizona
- Abbott Ventricular Tachycardia PAS — Naples, Florida
- Cardiac Radioablation for VT — Royal Oak, Michigan
- Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial — Ottawa, Ontario
- Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm — Rochester, Minnesota
- Trial in Arrhythmia Radioablation for Ventricular Tachycardia: Single Fraction vs Three Fractions — New York, New York
Explore by condition: All Ventricular Tachycardia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.