Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001) (NCT05853367)
A Phase 1/1b Open-label, Multicenter Clinical Study of MK-0472 as Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors.
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess the efficacy, safety, and tolerability of MK-0472 administered as monotherapy and in combination with pembrolizumab (MK-3475) or MK-1084 in participants with histologically or cytologically confirmed diagnosis of advanced/metastatic solid tumors.
Who can join: Review the eligibility criteria below.
Location: Northwestern Memorial Hospital ( Site 0002) — Chicago, Illinois
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (25 Sites)
- Northwestern Memorial Hospital ( Site 0002) — Chicago, Illinois
- The University of Louisville, James Graham Brown Cancer Center ( Site 0004) — Louisville, Kentucky
- John Theurer Cancer Center at Hackensack University Medical Center ( Site 0001) — Hackensack, New Jersey
- Rutgers Cancer Institute of New Jersey ( Site 0005) — New Brunswick, New Jersey
- Princess Margaret Cancer Centre ( Site 0101) — Toronto, Ontario
- Centre Hospitalier de l'Université de Montréal-Unit for Innovative Therapies ( Site 0100) — Montreal, Quebec
- Département clinique de médecine de laboratoire du CHUM ( Site 0104) — Montreal, Quebec
- Centro de Estudios Clínicos SAGA ( Site 0701) — Santiago, Region M. de Santiago
- Fundacion Arturo Lopez Perez ( Site 0700) — Santiago, Region M. de Santiago
- Centro de Investigacion Clinicadela Universidad Catolica ( Site 0703) — Santiago, Region M. de Santiago
- Bradfordhill ( Site 0702) — Santiago, Region M. de Santiago
- Rambam Health Care Campus ( Site 0304) — Haifa,
- Shaare Zedek Medical Center ( Site 0303) — Jerusalem,
- Rabin Medical Center ( Site 0301) — Petah Tikva,
- Sheba Medical Center ( Site 0300) — Ramat Gan,
- Sourasky Medical Center ( Site 0302) — Tel Aviv,
- Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 0401) — Warsaw, Masovian Voivodeship
- Uniwersyteckie Centrum Kliniczne ( Site 0400) — Gdansk, Pomeranian Voivodeship
- Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 0501) — L'Hospitalet de Llobregat, Catalonia
- Centro Integral Oncologico Clara Campal-Hospital HM Universitario Sanchinarro-START Madrid, ( Site 0504) — Madrid, Madrid, Comunidad de
- Hospital Universitari Vall d'Hebron ( Site 0500) — Barcelona,
- Hospital Virgen del Rocio ( Site 0503) — Seville,
- Hôpitaux Universitaires de Genève (HUG) ( Site 0202) — Geneva, Canton of Geneva
- Cantonal Hospital St.Gallen-Oncology & Hematology ( Site 0201) — Sankt Gallen, Canton of St. Gallen
- Ospedale Regionale Bellinzona e Valli ( Site 0200) — Bellinzona, Canton Ticino
📞 Contact the Study Coordinator
Phone: (855) 692-6482
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Metastatic Solid Tumors
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- A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors — Santa Rosa, California
- The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia. — Rochester, Minnesota
- A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors. — Nashville, Tennessee
- SLV-324 Treatment of Metastatic Solid Tumors — Newport Beach, California
Explore by condition: All Metastatic Solid Tumors clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.