IKS014 in Advanced Solid Tumors That Express HER2 (NCT05872295)
A Phase 1 Dose Escalation Trial to Determine the Safety, Tolerance, Maximum Tolerated Dose, and Preliminary Antineoplastic Activity of IKS014, a HER2-Targeting Antibody Drug Conjugate (ADC), in Participants With Advanced HER2+ Solid Tumors
🩺 Plain-English Summary (8th-Grade Level)
This study will evaluate the recommended dose for further clinical development, safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of IKS014, a HER2 targeting antibody-drug conjugate, in patients with advanced solid tumors.
Who can join: Review the eligibility criteria below.
Location: Hoag Memorial Hospital Presbyterian — Newport Beach, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (13 Sites)
- Hoag Memorial Hospital Presbyterian — Newport Beach, California
- Dana Farber Cancer Institute — Boston, Massachusetts
- Tennessee Oncology — Nashville, Tennessee
- START Dallas - Fort Worth — Fort Worth, Texas
- Concord Repatriation General Hospital Medical Oncology Clinical Trials Unit — Concord, New South Wales
- Macquarie University — Sydney, New South Wales
- Westmead Hospital — Westmead, New South Wales
- Peninsula & South Eastern Haematology and Oncology Group (PSEHOG) — Frankston, Victoria
- Alfred Health — Melbourne, Victoria
- Linear Clinical Research — Nedlands, Western Australia
- Auckland City Hospital — Auckland,
- National Cancer Centre Singapore — Singapore,
- Tan Tock Seng Hospital — Singapore,
📞 Contact the Study Coordinator
Phone: (615) 975-7776
Email: david.browning@iksuda.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.