iMmune SignAtures and Clinical outComes in AP (NCT05878236)
iMmune SignAtures and Clinical outComes in Acute Pancreatitis: the MoSAIC Study
🩺 Plain-English Summary (8th-Grade Level)
The MoSAIC study is a prospective, observational study designed to develop an early prediction tool for severe acute pancreatitis (SAP) and define a distinct immunologic profile compared to moderate acute pancreatitis (MAP). The aims are to validate a new multi-cytokine panel for early prediction of SAP and to identify the specific immune cells that correspond with cytokine signatures in early acute pancreatitis to characterize the immune pathways driving the development of SAP. Participants will provide blood samples and complete patient surveys and interviews within 36 hours of hospital presentation, at 48 hours, and hospital day 7 (if admitted). Data on hospital stay, medical history, clinical course, and severity of disease will be collected.
Who can join: Review the eligibility criteria below.
Location: University of Southern California — Los Angeles, California
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
- CyTOF Analysis (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- University of Southern California — Los Angeles, California
- University of Illinois Chicago — Chicago, Illinois
- The Ohio State University — Columbus, Ohio
- University of Pittsburgh — Pittsburgh, Pennsylvania
- Benaroya Research Institute — Seattle, Washington
📞 Contact the Study Coordinator
Phone: (614) 685-3619
Email: zoe.krebs@osumc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Acute Pancreatitis
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- Diabetes RElated to Acute Pancreatitis and Its Mechanisms — Los Angeles, California
- Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase — Charlotte, North Carolina
- DEciphering CIrculating SIgnatures Of Infected Pancreatic Necrosis — Minneapolis, Minnesota
- A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis — Little Rock, Arkansas
Explore by condition: All Acute Pancreatitis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.