🏛️ Verified NIH Record • Updated 2026-08-12
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD) (NCT05878769)
A Phase III Open-Label Extension Study to Evaluate the Long-Term Safety of Astegolimab in Patients With Chronic Obstructive Pulmonary Disease
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Hoffmann-La Roche
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess the long-term safety and to explore the efficacy of astegolimab in participants with chronic obstructive pulmonary disease (COPD) who have completed the 52-week placebo-controlled treatment period in parent studies GB43311 or GB44332.
Who can join: Review the eligibility criteria below.
Location: UAB Lung Health Center — Birmingham, Alabama
Age range: 40 Years to 90 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (481 Sites)
Showing the first 25 of 481 sites.
- UAB Lung Health Center — Birmingham, Alabama
- SEC Clinical Research LLC - Dothan 2 - ClinEdge - PPDS — Dothan, Alabama
- Jasper Summit Research LLC — Jasper, Alabama
- Pulmonary Associates of Mobile PC — Mobile, Alabama
- Pulmonary Associates Deer Valley Office — Phoenix, Arizona
- AES - DRS - Synexus Clinical Research US, Inc. - Tucson — Tucson, Arizona
- Kern Allergy and Medical Research — Bakersfield, California
- Cadena Care Institute, LLC — Poway, California
- Apex Clinical Research — San Diego, California
- St Francis Medical Institute ClinEdge PPDS — Clearwater, Florida
- Finlay Medical Research Corporation — Greenacres City, Florida
- Flourish Research - Leesburg - PPDS — Leesburg, Florida
- Advanced Pulmonary Research Institute — Loxahatchee Groves, Florida
- San Marcus Research Clinic Inc. — Miami, Florida
- Finlay Medical Research Corporation — Miami, Florida
- Oceane7 Medical & Research Center, Inc. — Miami, Florida
- Research Institute of South Florida Inc — Miami, Florida
- Diverse Clinical Research, LLC — Miami, Florida
- Central Florida Pulmonary Group, PA — Orlando, Florida
- Florida Institute for Clinical Research, LLC — Orlando, Florida
- Flourish Research - Orlando - PPDS — Winter Park, Florida
- Pivotal Research Solutions — Stonecrest, Georgia
- Northwestern Center for Clinical Research — Chicago, Illinois
- ASHA Clinical Research - ClinEdge - PPDS — Hammond, Indiana
- Best Clinical Trials — New Orleans, Louisiana
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Chronic Obstructive Pulmonary Disease
- Electronic Cigarette-derived Oxidants and Cardiopulmonary Effects — Hershey, Pennsylvania
- A Study to Investigate Long-term Safety and Tolerability of Itepekimab in Participants With COPD — Chandler, Arizona
- Inhaled Corticosteroids (ICS) on Pulmonary Endothelial Function in COPD — Miami, Florida
- A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD — Bakersfield, California
- Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease — Birmingham, Alabama
Explore by condition: All Chronic Obstructive Pulmonary Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.