๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-04-09

A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies (NCT05885555)

A Phase 2 Study to Evaluate the Efficacy and Safety of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least a Corticosteroid and a Thrombopoietin Receptor Agonist (TPO-RA)

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the therapeutic efficacy, safety and tolerability of ianalumab in adult patients with primary ITP previously treated with at least one corticosteroid and one TPO-RA.

Who can join: Review the eligibility criteria below.

Location: Massachusetts General Hospital โ€” Boston, Massachusetts

Age range: 18 Years to 100 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (24 Sites)

  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • Beth Israel Deaconess Med Center โ€” Boston, Massachusetts
  • Novartis Investigative Site โ€” CABA,
  • Novartis Investigative Site โ€” Garran, Australian Capital Territory
  • Novartis Investigative Site โ€” Melbourne, Victoria
  • Novartis Investigative Site โ€” Wuhan, Hubei
  • Novartis Investigative Site โ€” Beijing,
  • Novartis Investigative Site โ€” Jinan,
  • Novartis Investigative Site โ€” Toulouse,
  • Novartis Investigative Site โ€” Dresden, Saxony
  • Novartis Investigative Site โ€” Jena, Thuringia
  • Novartis Investigative Site โ€” Giessen,
  • Novartis Investigative Site โ€” Torino, TO
  • Novartis Investigative Site โ€” Johor Bahru,
  • Novartis Investigative Site โ€” Katowice,
  • Novartis Investigative Site โ€” Seoul,
  • Novartis Investigative Site โ€” Barcelona, Catalonia
  • Novartis Investigative Site โ€” Aydin, Efeler
  • Novartis Investigative Site โ€” Istanbul, Fatih
  • Novartis Investigative Site โ€” Edirne, Merkez
  • Novartis Investigative Site โ€” Izmir,
  • Novartis Investigative Site โ€” Kocaeli,
  • Novartis Investigative Site โ€” Glasgow,
  • Novartis Investigative Site โ€” London,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—