๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-28

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers (NCT05891171)

A Phase 1/1b Study to Evaluate the Safety and Tolerability of AB598 Monotherapy and Combination Therapy in Participants With Advanced Malignancies

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Arcus Biosciences, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Phoenix, Arizona

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (14 Sites)

  • Research Site โ€” Phoenix, Arizona
  • Research Site โ€” Jacksonville, Florida
  • Research Site โ€” Lake City, Florida
  • Research Site โ€” Hinsdale, Illinois
  • Research Site โ€” Detroit, Michigan
  • Research Site โ€” Rochester, Minnesota
  • Research Site โ€” New Brunswick, New Jersey
  • Research Site โ€” Canton, Ohio
  • Research Site โ€” Cleveland, Ohio
  • Research Site โ€” Irving, Texas
  • Research Site โ€” Fairfax, Virginia
  • Research Site โ€” Adelaide,
  • Research Site โ€” Tainan,
  • Research Site โ€” Taipei,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Advanced Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—