🏛️ Verified NIH Record • Updated 2025-04-07
Longitudinal ctDNA Surveillance for Older Women With ER+ Breast Cancer Who Omit Surgery (NCT05914792)
Longitudinal ctDNA Monitoring in Older Women With ER+ Breast Cancer Who Forego Upfront Surgery in Favor of Primary Endocrine Therapy
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: University of Pittsburgh
🩺 Plain-English Summary (8th-Grade Level)
This prospective study recruits patients with ER+/HER2-, non-metastatic breast cancer who omit upfront surgery in favor of primary endocrine therapy for sample collection and prospective circulating tumor DNA (ctDNA) measurement to guide disease surveillance.
Who can join: Review the eligibility criteria below.
Location: UPMC Magee Womens Hospital - Surgical Oncology — Pittsburgh, Pennsylvania
Age range: 70 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- UPMC Magee Womens Hospital - Surgical Oncology — Pittsburgh, Pennsylvania
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.