Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (NCT05924477)
🩺 Plain-English Summary (8th-Grade Level)
Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked, randomized clinical trial. The purpose of this study is to compare glaucoma drainage device implantation in the anterior chamber (front part of the eye) and sulcus (small space between iris and front chamber of the eye) in efforts to minimize cell loss in the eye.
Who can join: Review the eligibility criteria below.
Location: University of California San Francisco — San Francisco, California
Age range: 18 Years
🧪 Interventions in This Study
- Sulcus tube placement (PROCEDURE)
- Anterior chamber (AC) tube placement (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- University of California San Francisco — San Francisco, California
- Diablo Eye Associates — Walnut Creek, California
- Bascom Palmer Eye Institute — Miami, Florida
- Wilmer Eye Institute, Johns Hopkins University — Baltimore, Maryland
- Massachusetts Eye and Ear — Boston, Massachusetts
- University of Buffalo/State University of New York — Buffalo, New York
- University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
- Prism Eye Institute, University of Toronto — Toronto,
📞 Contact the Study Coordinator
Phone: (215) 615-1514
Email: gsying@pennmedicine.upenn.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Glaucoma
- Novel Markers for Detecting Early Progression of Glaucoma — Halifax, Nova Scotia
- Electrical Stimulation for the Treatment of Glaucoma — Palo Alto, California
- Visual Field Analysis With Artificial Intelligence — Alexandria, Virginia
- Anterior Segment Optical Coherence Tomography Microstent Positioning — Murray, Utah
- Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination — Santa Rosa de Copán,
- Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma. — Glendale, Arizona
Explore by condition: All Glaucoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.