Who is eligible for clinical trial NCT05932745?

Participants must meet protocol criteria for Nicotine Use Disorder. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT05932745 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-06-12

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0 (NCT05932745)

Examining Appeal and Addiction Potential of Novel E-cigarette Constituents Among Adults

🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: Yale University

🩺 Plain-English Summary (8th-Grade Level)

This study is an examination of the influence of cooling components of WS-3, WS-23, and menthol on the appeal and addiction potential of nicotine-containing e-liquids among adults.

Who can join: Review the eligibility criteria below.

Location: JB Pierce Lab — New Haven, Connecticut

Age range: 18 Years

🧪 Interventions in This Study

E-liquid coolant (No WS-3) for non-menthol (1) (OTHER)
E-liquid coolant (No WS-3) for low (0.1%) menthol (1) (OTHER)
E-liquid coolant (No WS-3) for high (2.0%) menthol (1) (OTHER)
E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2) (OTHER)
E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2) (OTHER)
E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2) (OTHER)
E-liquid coolant (High [2.0%] WS-3) for non-menthol (3) (OTHER)
E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3) (OTHER)
E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3) (OTHER)
E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4) (OTHER)
E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4) (OTHER)
E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4) (OTHER)
E-liquid coolant (High [2.0%] WS-23) for non-menthol (5) (OTHER)
E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5) (OTHER)
E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5) (OTHER)
E-liquid coolant (4% WS-23) for non-menthol (6) (OTHER)
E-liquid coolant (4% WS-23) for low (0.1%) menthol (6) (OTHER)
E-liquid coolant (4% WS-23) for high (2.0%) menthol (6) (OTHER)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (1 Sites)

JB Pierce Lab — New Haven, Connecticut

📞 Contact the Study Coordinator

Phone: (203) 974-7607

Email: danielle.davis@yale.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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Explore by condition: All Nicotine Use Disorder clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Contact the study coordinator using the phone/email above.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗