🏛️ Verified NIH Record • Updated 2026-05-08

Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study (NCT05935358)

Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study (NuPOWER)

🟢 Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: Octapharma

🩺 Plain-English Summary (8th-Grade Level)

Recombinant factor VIII for the prevention of bleeding in patients with severe haemophilia A undergoing major surgery while receiving emicizumab prophylaxis

Who can join: Review the eligibility criteria below.

Location: UT Southwestern Medical Center — Dallas, Texas

Age range: 12 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (18 Sites)

  • UT Southwestern Medical Center — Dallas, Texas
  • University Hospital Centre Zagreb — Zagreb,
  • Helsinki University Hospital — Helsinki,
  • CHU de Nantes Hôtel-Dieu — Nantes,
  • CHRU de Tours — Tours,
  • Vivantes Klinikum im Friedrichshein (KFH) — Berlin,
  • Gerinnungszentrum Rhein-Ruhr — Duisburg,
  • Universitätsklinikum Hamburg Eppendorf (UKE) — Hamburg,
  • Christian Medical College Vellore — Vellore, Tamil Nadu
  • St. John's Medical College Hospital — Bengaluru,
  • Azienda Ospedaliera Pugliese Ciaccio — Catanzaro,
  • Azienda Ospedaliero Universitaria Careggi - Centro Emofilia — Florence,
  • Centro Trombosi e Malattie Emorragiche, ITCCS Humanitas Research Hospital — Milan,
  • Centre for Haemopilia, Institute for transfusion medicine of Republic of North Macedonia — Skopje,
  • Clinical Center for Serbia Belgrade — Belgrade,
  • Hospital Universitario La Paz — Madrid,
  • Hospital Universitario Virgen del Rocio — Seville,
  • St. James's University Hospital — Leeds,

📞 Contact the Study Coordinator

Phone: +41 554512141

Email: Sigurd.Knaub@octapharma.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗