🏛️ Verified NIH Record • Updated 2026-05-08
Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study (NCT05935358)
Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study (NuPOWER)
🟢 Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: Octapharma
🩺 Plain-English Summary (8th-Grade Level)
Recombinant factor VIII for the prevention of bleeding in patients with severe haemophilia A undergoing major surgery while receiving emicizumab prophylaxis
Who can join: Review the eligibility criteria below.
Location: UT Southwestern Medical Center — Dallas, Texas
Age range: 12 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (18 Sites)
- UT Southwestern Medical Center — Dallas, Texas
- University Hospital Centre Zagreb — Zagreb,
- Helsinki University Hospital — Helsinki,
- CHU de Nantes Hôtel-Dieu — Nantes,
- CHRU de Tours — Tours,
- Vivantes Klinikum im Friedrichshein (KFH) — Berlin,
- Gerinnungszentrum Rhein-Ruhr — Duisburg,
- Universitätsklinikum Hamburg Eppendorf (UKE) — Hamburg,
- Christian Medical College Vellore — Vellore, Tamil Nadu
- St. John's Medical College Hospital — Bengaluru,
- Azienda Ospedaliera Pugliese Ciaccio — Catanzaro,
- Azienda Ospedaliero Universitaria Careggi - Centro Emofilia — Florence,
- Centro Trombosi e Malattie Emorragiche, ITCCS Humanitas Research Hospital — Milan,
- Centre for Haemopilia, Institute for transfusion medicine of Republic of North Macedonia — Skopje,
- Clinical Center for Serbia Belgrade — Belgrade,
- Hospital Universitario La Paz — Madrid,
- Hospital Universitario Virgen del Rocio — Seville,
- St. James's University Hospital — Leeds,
📞 Contact the Study Coordinator
Phone: +41 554512141
Email: Sigurd.Knaub@octapharma.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Severe Hemophilia A
- A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis — Los Angeles, California
- A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors — Phoenix, Arizona
- A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A. — Los Angeles, California
Explore by condition: All Severe Hemophilia A clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.