๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-09

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF) (NCT05943535)

A Randomized, Double-blind, Placebo-controlled, Multinational, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: United Therapeutics

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Study RIN-PF-305 is designed to evaluate the safety and efficacy of inhaled treprostinil in subjects with progressive pulmonary fibrosis (PPF) over a 52-week period.

Who can join: Review the eligibility criteria below.

Location: UAB Lung Health Center โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (165 Sites)

Showing the first 25 of 165 sites.

  • UAB Lung Health Center โ€” Birmingham, Alabama
  • Banner University Medical Center Phoenix Lung Institute โ€” Phoenix, Arizona
  • Norton Thoracic Institute โ€” Phoenix, Arizona
  • Peter Morton Medical Building โ€” Los Angeles, California
  • NewportNativeMD, Inc. โ€” Newport Beach, California
  • University of California Irvine Medical Center โ€” Orange, California
  • Paradigm Clinical Research โ€” Redding, California
  • UC Davis Health Medical Center โ€” Sacramento, California
  • Paradigm Clinical Research โ€” San Diego, California
  • Stanford University Medical Center โ€” Stanford, California
  • Georgetown University Hospital โ€” Washington D.C., District of Columbia
  • Ascension Medical Group St. Vincent's Lung Institute โ€” Jacksonville, Florida
  • Mayo Clinic โ€” Jacksonville, Florida
  • TGH/USF Center for Advanced Lung Disease and Lung Transplant โ€” Tampa, Florida
  • Cleveland Clinic Florida โ€” Weston, Florida
  • The Emory Clinic โ€” Atlanta, Georgia
  • Northwestern Memorial Hospital, Clinical Research Unit โ€” Chicago, Illinois
  • Rush University Medical Center Outpatient Pulmonary Clinic โ€” Chicago, Illinois
  • UI Health Hospital โ€” Chicago, Illinois
  • Loyola University Medical Center โ€” Maywood, Illinois
  • University of Kansas Medical Center โ€” Kansas City, Kansas
  • University of Kentucky โ€” Lexington, Kentucky
  • University of Louisville Healthcare Outpatient Research Clinic โ€” Louisville, Kentucky
  • Tulane Medical Center โ€” New Orleans, Louisiana
  • Johns Hopkins Asthma and Allergy Center โ€” Baltimore, Maryland

๐Ÿ“ž Contact the Study Coordinator

Phone: (919) 485-8350

Email: clinicaltrials@unither.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—