Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma (NCT05948475)
A Phase III, Randomized, Controlled, Global Multicenter Study to Evaluate the Efficacy and Safety of Oral Tinengotinib VS Physician's Choice in Subjects With FGFR-altered, Chemotherapy- and FGFR Inhibitor-Cholangiocarcinoma
๐ฉบ Plain-English Summary (8th-Grade Level)
This study is a Phase III, Randomized, Controlled, Global Multicenter Study to Evaluate the Efficacy and Safety of Oral Tinengotinib versus Physician's Choice in Subjects with Fibroblast Growth Factor Receptor (FGFR)-altered, Chemotherapy- and FGFR Inhibitor-Refractory/Relapsed Cholangiocarcinoma
Who can join: Review the eligibility criteria below.
Location: UCLA Medical Center โ Santa Monica, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (87 Sites)
Showing the first 25 of 87 sites.
- UCLA Medical Center โ Santa Monica, California
- Stanford Cancer Center โ Stanford, California
- The University of Kansas Cancer Center โ Westwood, Los Angeles, California
- Mount Sinai Comprehensive Cancer Center โ Miami Beach, Florida
- The University of Chicago Hospitals โ Chicago, Illinois
- UMass Memorial Medical Center โ Worcester, Massachusetts
- University of Michigan โ Ann Arbor, Michigan
- Henry Ford โ Detroit, Michigan
- University of Minnesota- Masonic Cancer Center, M Health Fairview โ Minneapolis, Minnesota
- Roswell Park Comprehensive Cancer Center โ Buffalo, New York
- Messino Cancer Centers โ Asheville, North Carolina
- University Hospitals Cleveland Medical Center โ Cleveland, Ohio
- Tennessee Oncology- Nashville โ Nashville, Tennessee
- Vanderbilt-Ingram Cancer Center โ Nashville, Tennessee
- University of Texas Southwestern Medical Center โ Dallas, Texas
- Texas Oncology-Sammons Cancer Center โ Dallas, Texas
- The University of Texas MD Anderson Cancer Center โ Houston, Texas
- University of Virginia Cancer Center โ Charlottesville, Virginia
- Medical College of Wisconsin โ Milwaukee, Wisconsin
- Ordensklinikum Linz GmbH โ Linz,
- Landesklinikum Wiener Neustadt โ Wiener Neustadt,
- Universitair Ziekenhuis Antwerpen โ Antwerp,
- Universitair Ziekenhuis Gent โ Ghent,
- Universitair Ziekenhuis Leuven โ Leuven,
- Institut Sainte Catherine - Institut du Cancer Avignon Provence โ Avignon,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cholangiocarcinoma
- Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations โ Phoenix, Arizona
- An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma โ Yerevan,
- [18F]FTT Positron Emission Tomography/Computed Tomography to Predict Treatment Response in Patients Scheduled to Receive Gemcitabine, Cisplatin, and Durvalumab for Newly Diagnosed Cholangiocarcinoma โ Seattle, Washington
- Cell-Surface Plectin in the Diagnosis of Cholangiocarcinoma from ERCP-directed Biliary Samples โ Charlottesville, Virginia
- Implementing a Randomized Control Trial to Test the Expanded Web-based Decision Aid โ St Louis, Missouri
Explore by condition: All Cholangiocarcinoma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.