๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-03

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial (NCT05958342)

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Jason Sperry

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) Trial is a proposed 4 year, double-blind, mutli-center, prehospital and early in hospital phase randomized trial designed to determine the efficacy and safety of prehospital calcium and early in hospital vasopressin in patients at risk of hemorrhagic shock.

Who can join: Review the eligibility criteria below.

Location: Chandler Regional Medical Center โ€” Chandler, Arizona

Age range: 18 Years to 90 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (16 Sites)

  • Chandler Regional Medical Center โ€” Chandler, Arizona
  • University of Arizona โ€” Tucson, Arizona
  • University of Arkansas for Medical Sciences โ€” Little Rock, Arkansas
  • Zuckerberg San Francisco General Hospital and Trauma Center at University of California, San Francisco โ€” San Francisco, California
  • Denver Health Medical Center โ€” Denver, Colorado
  • University of Miami โ€” Miami, Florida
  • University of Maryland, Baltimore โ€” Baltimore, Maryland
  • Hennepin County Medical Center โ€” Minneapolis, Minnesota
  • University of Missouri Health Care โ€” Columbia, Missouri
  • University of New Mexico โ€” Albuquerque, New Mexico
  • The Ohio State University Wexner Medical Center โ€” Columbus, Ohio
  • Mount Carmel East Hospital โ€” Columbus, Ohio
  • Allegheny Health Network โ€” Pittsburgh, Pennsylvania
  • University of Pittsburgh โ€” Pittsburgh, Pennsylvania
  • Texas Tech University Health Sciences Center โ€” Lubbock, Texas
  • University of Washington Harborview Medical Center โ€” Seattle, Washington

๐Ÿ“ž Contact the Study Coordinator

Phone: (412) 802-8270

Email: sperryjl@upmc.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Trauma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—