πŸ›οΈ Verified NIH Record β€’ Updated 2026-06-10

R-2487 in Patients With Rheumatoid Arthritis (NCT05961592)

A Single and Repeat Dosing Study of the Safety, Drug Exposure and Clinical Activity of R-2487 in Patients With Rheumatoid Arthritis

🟒 Recruiting Phase1 πŸ’Š Investigational Drug / Biologic Sponsor: Rise Therapeutics LLC

🩺 Plain-English Summary (8th-Grade Level)

The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-2487) in patients with Rheumatoid Arthritis. Patients will take an oral dosage of probiotic (R-2487) and physicians will assess and measure their Rheumatoid Arthritis. Blood and fecal evaluations of inflammation and assessment of probiotic (R-2487) on fecal level will also be measured.

Who can join: Review the eligibility criteria below.

Location: University of California, San Diego β€” San Diego, California

Age range: 18 Years to 75 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (6 Sites)

  • University of California, San Diego β€” San Diego, California
  • St.Jude Clinical Research β€” Doral, Florida
  • AP Medical Research β€” Miami, Florida
  • Edward Jenner Research β€” Plantation, Florida
  • Altoona Center for Research β€” Duncansville, Pennsylvania
  • Prolato Clinical Research Center β€” Houston, Texas

πŸ“ž Contact the Study Coordinator

Phone: (650) 417-8556

Email: jstephens@risetherapeutics.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—