๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-02-03

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma (NCT05962242)

Circulating Tumor Modified HPV DNA-Guided Radiotherapy De-intensification of the Elective Neck (RaDEN) in Squamous Cell Carcinoma of the Head and Neck

๐ŸŸข Recruiting Phase2 ๐Ÿ“‹ Clinical Research Protocol Sponsor: University of Virginia

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The study will evaluate the safety and effectiveness of a lower than standard dose of radiation for definitive or adjuvant treatment of head and neck squamous cell carcinomas.

Who can join: Review the eligibility criteria below.

Location: Miami Cancer Institute โ€” Miami, Florida

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • Radiation Therapy (RADIATION)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (5 Sites)

  • Miami Cancer Institute โ€” Miami, Florida
  • University of Virginia โ€” Charlottesville, Virginia
  • Eastern Virginia Medical School โ€” Norfolk, Virginia
  • Bon Secours โ€” Richmond, Virginia
  • Virginia Commonwealth University โ€” Richmond, Virginia

๐Ÿ“ž Contact the Study Coordinator

Phone: (434) 243-0008

Email: UVARADONCClinicalTrials@uvahealth.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Squamous Cell Carcinoma of the Oropharynx

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—