Childhood Trauma, Exercise, and Cognition (NCT05972265)
Exercise and Cognition in Middle-Aged Adults With Histories of Childhood Trauma and Cognitive Complaints
🩺 Plain-English Summary (8th-Grade Level)
This study aims to identify and compare the effects of acute and chronic exercise interventions on cognition in middle-aged adults with cognitive complaints and a history of abuse or neglect in childhood. Each participant will be enrolled in the study for up to 78 days, in five parts following verification that the participant meets criteria to be included in the study: 1) initial assessment; 2) first acute exercise condition in lab, symptom measures, and neuropsychological testing; 3) second acute exercise condition in lab, symptom measures, and neuropsychological testing; and 4) 9-week exercise intervention or activity as usual outside of lab, with interview, symptom measures, and neuropsychological testing at three-week intervals.
Who can join: Review the eligibility criteria below.
Location: University of Texas at Austin — Austin, Texas
Age range: 40 Years to 60 Years
🧪 Interventions in This Study
- Moderate Intensity Exercise (one day) (BEHAVIORAL)
- Placebo - Light Intensity Exercise (one day) (BEHAVIORAL)
- Moderate Intensity Exercise (9 wks) (BEHAVIORAL)
- Day 1 Assessments (OTHER)
- Symptom Measures and Neuropsychological Tests (OTHER)
- Day 36 Assessments (OTHER)
- Day 57 Assessments (OTHER)
- Day 78 Assessments (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Texas at Austin — Austin, Texas
📞 Contact the Study Coordinator
Phone: (512) 954-5510
Email: erin.logue@austin.utexas.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Adverse Childhood Experiences
- Playing Playfully to Overcome Adversity — Fairfield, Connecticut
- The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments — Irvine, California
- ACEs, SIRT1, and Premature Vascular Aging in Humans — Iowa City, Iowa
- Building Resilient Families — Loma Linda, California
- Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking — Durham, North Carolina
Explore by condition: All Adverse Childhood Experiences clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.