๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-07-30

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial (NCT05991453)

๐ŸŸข Recruiting Observational / Diagnostic ๐Ÿ“‹ Clinical Research Protocol Sponsor: Washington University School of Medicine

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries

Who can join: Review the eligibility criteria below.

Location: University of Arkansas for Medical Sciences (UAMS) โ€” Little Rock, Arkansas

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • Anesthetic technique Propofol TIVA (OTHER)
  • Anesthetic technique inhaled agent (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (20 Sites)

  • University of Arkansas for Medical Sciences (UAMS) โ€” Little Rock, Arkansas
  • University of California San Francisco โ€” San Francisco, California
  • Stanford University โ€” Stanford, California
  • Yale School of Medicine โ€” New Haven, Connecticut
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • Brigham & Women's โ€” Boston, Massachusetts
  • University of Michigan โ€” Ann Arbor, Michigan
  • Henry Ford Health โ€” Detroit, Michigan
  • Washington University School of Medicine โ€” St Louis, Missouri
  • Dartmouth Hitchcock Medical Center โ€” Lebanon, New Hampshire
  • NYU Langone โ€” New York, New York
  • Weill Cornell Medicine โ€” New York, New York
  • Duke University โ€” Durham, North Carolina
  • Wake Forest โ€” Winston-Salem, North Carolina
  • Oregon Health and Sciences University โ€” Portland, Oregon
  • University of Pennsylvania โ€” Philadelphia, Pennsylvania
  • University of Texas - MD Anderson โ€” Houston, Texas
  • University of Utah - Medical โ€” Salt Lake City, Utah
  • UVA Health โ€” Charlottesville, Virginia
  • University of Washington โ€” Seattle, Washington

๐Ÿ“ž Contact the Study Coordinator

Phone: (314) 286-1024

Email: goodl@wustl.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Surgery-Complications

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—