Objective Concussion Assessment Using MRI and Metabolomics (NCT05993351)
Correlating Advanced MRI Techniques With Neuropsychological Analysis and Immunosensing Assays for Assessment of Sport-related Mild Traumatic Brain Injuries (mTBI)
🩺 Plain-English Summary (8th-Grade Level)
Mild traumatic brain injury (mTBI), also referred to as concussions, affect millions of people around the world and can cause harmful long term effects. Unfortunately, concussions can be hard to diagnose and many people have lasting post-concussion symptoms such as headaches, difficulty concentrating, and light sensitivity. Recent studies have shown that advanced magnetic resonance imaging (MRI) techniques can identify subtle brain changes caused by a concussion. This study aims to track concussions over time measuring MRI brain scans and post-concussion symptoms to gain a better understand how the brain is affected in comparison to symptoms.
Who can join: Review the eligibility criteria below.
Location: Imaging Research Center at St. Joseph's Healthcare Hamilton — Hamilton, Ontario
Age range: 9 Years to 50 Years
🧪 Interventions in This Study
- Magnetic resonance imaging (MRI) (DIAGNOSTIC_TEST)
- Urine and saliva samples (DIAGNOSTIC_TEST)
- Questionnaires (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Imaging Research Center at St. Joseph's Healthcare Hamilton — Hamilton, Ontario
📞 Contact the Study Coordinator
Phone: (905) 525-9140
Email: nosewor@mcmaster.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Concussion, Brain clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.