Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma (NCT05998642)
A Phase 2 Study of Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary Central Nervous System Lymphoma
🩺 Plain-English Summary (8th-Grade Level)
This study is being done to answer the following question: Can the addition of a new drug to the usual treatment lower the chance of primary central nervous system lymphoma growing or spreading? This study is being done to find out if this approach is better or worse than the usual approach for this type of cancer. The usual approach is defined as the care most people get for Primary Central Nervous System Lymphoma (PCNSL).
Who can join: Review the eligibility criteria below.
Location: Arthur J.E. Child Comprehensive Cancer Centre — Calgary, Alberta
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- Arthur J.E. Child Comprehensive Cancer Centre — Calgary, Alberta
- BCCA - Vancouver — Vancouver, British Columbia
- Juravinski Cancer Centre at Hamilton Health Sciences — Hamilton, Ontario
- Ottawa Hospital Research Institute — Ottawa, Ontario
- University Health Network — Toronto, Ontario
- The Research Institute of the McGill University — Montreal, Quebec
- CHU de Quebec-Hopital l'Enfant-Jesus (HEJ) — Québec, Quebec
- Allan Blair Cancer Centre — Regina, Saskatchewan
📞 Contact the Study Coordinator
Phone: (613) 533-6430
Email: ahay@ctg.queensu.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.