Optimization of Cervical Cancer Screening Among Women Living With HIV in Latin American Countries (NCT06002126)
🩺 Plain-English Summary (8th-Grade Level)
Cervical cancer is a relatively common cancer among women living with human immunodeficiency virus (HIV). This study will test women for human papillomavirus (HPV) infection of the cervix. The main purpose of this study is to determine the best way to test for damaged areas of the cervix. Damaged areas of the cervix should be treated and removed to prevent cancer of the cervix. Women living with HIV (WLWH) in this study will be seen once, twice or three times in a year. Women will provide several samples related to screening for cervical cancer including a swab of the cervix, a self-collected swab of the vagina and urine. Women will have a detailed examination of the cervix called colposcopy and have a few biopsies, or small pinches of the cervix, to look for areas at risk for turning into cancer. If HPV of the cervix is found but treatment of the cervix is not indicated, women will return in 6 months and in 12 months to repeat these tests. Most women will only need 1 visit. Women found to have damaged areas of the cervix at risk for turning into cancer will be referred for treatment. This protocol will compare different tests to understand the best test to identify women at risk for cervical cancer.
Who can join: Review the eligibility criteria below.
Location: University of São Paulo — São Paulo, São Paulo
Age range: 25 Years to 65 Years
🧪 Interventions in This Study
- Xpert HPV (DIAGNOSTIC_TEST)
- QIAsure Methylation Test (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- University of São Paulo — São Paulo, São Paulo
- National Institute of Public Health, Mexico — Cuernavaca, Morelos
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cervix Cancer
- Cervix Hypoxia FAZA — Toronto, Ontario
- Intra-Pelvic Organ Motion for Cervix Cancer Patient Using Imaging — Toronto, Ontario
- Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies — Chapel Hill, North Carolina
- Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix) — Dallas, Texas
Explore by condition: All Cervix Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.