Attentional Mechanisms in SCD (NCT06002477)
Attentional Mechanisms of Cognitive Compensation in Subjective Cognitive Decline
๐ฉบ Plain-English Summary (8th-Grade Level)
This study will use an anticholinergic pharmacological probe to examine attention network function in SCD using EEG. The overall hypothesis is that in older adults with SCD, normal cognitive performance is maintained by compensatory attention network activity, supported by enhanced cholinergic function. The investigators anticipate that SCD will be associated with greater compensatory attention network activity and that disrupting this compensatory process through anticholinergic challenge will result in a greater negative effect on attentional performance (Attention Network Test, ANT) and attention network functioning (EEG) in older adults with greater subjective cognitive concern.
Who can join: Review the eligibility criteria below.
Location: Vanderbilt University Medical Center โ Nashville, Tennessee
Age range: 55 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- Vanderbilt University Medical Center โ Nashville, Tennessee
๐ Contact the Study Coordinator
Phone: (615) 936-4559
Email: kimberly.albert@vumc.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Subjective Cognitive Decline
- Impact of a Cognitive Intervention Enriched With Leisure Activities in Persons With Subjective Cognitive Decline โ Toronto, Ontario
- The Lifestyle Exercise and Diet Trial (LEAD) 2.0 โ Waterloo, Ontario
- Developing a Peer Support Intervention for Depression in SCD โ Boston, Massachusetts
- ฮ-OHB Supplementation and Brain Health in Older Adults โ Hamilton, Ontario
Explore by condition: All Subjective Cognitive Decline clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.