A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. (NCT06022029)
A Phase 1 Dose-Escalation and Expansion Study of Intratumorally Administered ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas
🩺 Plain-English Summary (8th-Grade Level)
A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or recommended dose for expansion (RDE) of intratumoral ONM-501 as monotherapy and in combination with a PD-1 checkpoint inhibitor in patients with advanced solid tumors and lymphomas.
Who can join: Review the eligibility criteria below.
Location: California Research Institute — Los Angeles, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- California Research Institute — Los Angeles, California
- BRCR Global — Tamarac, Florida
- Gabrail Cancer Center Research — Canton, Ohio
- Ohio State University — Columbus, Ohio
- Allegheny Health Network — Pittsburgh, Pennsylvania
- UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania
- University of Texas Southwestern Medical Center — Dallas, Texas
- MD Anderson Cancer Center — Houston, Texas
- Virginia Cancer Specialists, PC — Fairfax, Virginia
- St Vincent's Hospital — Darlinghurst, New South Wales
- Cancer Care Wollongong — Wollongong, New South Wales
- University of the Sunshine Coast Clinical Trials — Buderim, Queensland
- Tasman Oncology Research — Southport, Queensland
- Princess Alexandra Hospital | Metro South Health — Woolloongabba, Queensland
- Southern Oncology Clinical Research Unit — Bedford Park, South Australia
- St John of God Subiaco Hospital — Subiaco, Western Australia
📞 Contact the Study Coordinator
Phone: (682) 285-1411
Email: trials@onconanomed.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.