Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment (NCT06033274)
Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment: the TRIPLACE Registry
🩺 Plain-English Summary (8th-Grade Level)
The field of transcatheter tricuspid valve replacement (TTVR) is rapidly emerging and data on this topic are scarce. Particularly, little is known about which patients are at greatest risk of procedural complications, such as the timing and onset of conduction disturbances necessitating permanent pacemaker implantation, and how such patients are managed. On this background, the TRIPLACE Registry - an investigator-initiated global multicenter registry - is aimed at better understanding the safety and efficacy of orthotopic TTVR.
Who can join: Review the eligibility criteria below.
Location: Arizona Heart Hospital (Biltmore Cardiology) — Phoenix, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (21 Sites)
- Arizona Heart Hospital (Biltmore Cardiology) — Phoenix, Arizona
- Columbia University Irving Medical Center — New York, New York
- Montefiore Medical Center — The Bronx, New York
- Cleveland Clinic — Cleveland, Ohio
- Oregon Health & Science University — Portland, Oregon
- St. Paul's Hospital — Vancouver, British Columbia
- St Michael's Hospital, University of Toronto — Toronto, Ontario
- Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada — Québec, Quebec
- Rigshospitalet, Copenhagen University Hospital — Copenhagen,
- Chu De Bordeaux - Haut-Lévêque Hospital — Bordeaux, Pessac
- Centre Hospitalier Universitaire de Lille — Lille,
- Clinique Pasteur Toulouse — Toulouse,
- Heart and Diabetes Centre, North Rhine-Westphalia (NRW), Ruhr-University — Bad Oeynhausen,
- Heart Center Cologne, University of Cologne — Cologne,
- Cardiovascular Center (CVC) Frankfurt, Division of Cardiology — Frankfurt,
- University Heart and Vascular Center, Department of Cardiology — Hamburg,
- University Heart Center, Schleswig-Holstein University — Lübeck,
- Medical Clinic and Polyclinic, University Hospital of Munich (LMU Klinikum) — Munich,
- San Raffaele University Hospital — Milan,
- Centro Cardiologico Monzino IRCCS — Milan,
- University Hospital Alvaro Cunqueiro (CHUVI) — Vigo, Pontevedra
📞 Contact the Study Coordinator
Phone: (718) 904-3388
Email: ascotti@montefiore.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Tricuspid Regurgitation
- TRILUMINATE Pivotal Trial — Birmingham, Alabama
- TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I) — Phoenix, Arizona
- TTVR Early Feasibility Study — Birmingham, Alabama
- Clinical Study of Edwards Cardioband FIT Valve Repair System — Chicago, Illinois
- Laplace Early Feasibility Study - Canada — Ottawa, Ontario
- Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System — Tucson, Arizona
Explore by condition: All Tricuspid Regurgitation clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.