🏛️ Verified NIH Record • Updated 2026-01-09

A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma (NCT06054555)

A Randomized, Double-Blind Study Evaluating the Efficacy, Safety, and Immunogenicity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Treatment-Naïve Unresectable or Metastatic Melanoma

🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Amgen

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to assess the efficacy, safety, and immunogenicity of ABP 206 compared with Nivolumab in Subjects with Treatment-Naïve Unresectable or Metastatic Melanoma.

Who can join: Review the eligibility criteria below.

Location: Cancer and Blood Specialty clinic — Long Beach, California

Age range: 18 Years to 99 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (180 Sites)

Showing the first 25 of 180 sites.

  • Cancer and Blood Specialty clinic — Long Beach, California
  • Fort Wayne Medical Oncology and Hematology - Office of Clinical Research — Fort Wayne, Indiana
  • Our Lady of the Lake Physicians Group-Medical Oncology-Woman's Pavilion — Baton Rouge, Louisiana
  • Oncology Hematology Associates — Springfield, Missouri
  • Hematology-Oncology Associates of Central New York, P.C. (HOA) - East Syracuse - CCOP — East Syracuse, New York
  • Centro de Investigaciones Médicas y Desarrollo LC — Buenos Aires, Ciudad Autónoma de Buenos Aire
  • Centro De Investigaciones Medicas Mar Del Plata (CIMMDP) - Rheumatology — Mar Del Plata, Río Negro Province
  • Clínica Viedma - Oncology — Viedma, Río Negro Province
  • Instituto De Oncologia De Rosario — Rosario, Santa Fe Province
  • ISIS Clinica Especializada — Santa Fe,
  • Clinical Center University of Sarajevo - Clinic of Oncology — Sarajevo, Kanton Sarajevo
  • University Clinical Center of Republic of Srpska — Banja Luka, Republika Srpska
  • University Clinical Center Tuzla - Oncology, Hematology and Radio — Tuzla, Tuzlanski Kanton
  • Cantonal hospital Zenica - Oncology — Zenica, Zeničko-dobojski Kanton
  • Dr. Everett Chalmers Hospital - Oncology — Fredericton, New Brunswick
  • Centro de Investigacion y Desarrollo Oncologico — Temuco, Araucania
  • IC La Serena Research — La Serena, Coquimbo Region
  • Icegclinic Research & Care — Estacion Central, Santiago Metropolitan
  • Oncocentro Apys — Valparaíso, Valparaiso
  • University Hospital Centre Zagreb - Oncology department — Zagreb, City of Zagreb
  • Poliklinika Anova — Zagreb, City of Zagreb
  • Klinicki bolnicki centar Osijek — Osijek, Osjecko-baranjska Županija
  • FN Hradec Kralove - Klinika onkologie a radioterap — Hradec Kralove, Moravian-Silesian Region
  • Vseobecna fakultni nemocnice v Praze - Dermatovenerologicka — Prague,
  • Tartu University Hospital - Oncology — Tartu, Tartu

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Melanoma clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗