🏛️ Verified NIH Record • Updated 2026-01-09
A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma (NCT06054555)
A Randomized, Double-Blind Study Evaluating the Efficacy, Safety, and Immunogenicity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Treatment-Naïve Unresectable or Metastatic Melanoma
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Amgen
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess the efficacy, safety, and immunogenicity of ABP 206 compared with Nivolumab in Subjects with Treatment-Naïve Unresectable or Metastatic Melanoma.
Who can join: Review the eligibility criteria below.
Location: Cancer and Blood Specialty clinic — Long Beach, California
Age range: 18 Years to 99 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (180 Sites)
Showing the first 25 of 180 sites.
- Cancer and Blood Specialty clinic — Long Beach, California
- Fort Wayne Medical Oncology and Hematology - Office of Clinical Research — Fort Wayne, Indiana
- Our Lady of the Lake Physicians Group-Medical Oncology-Woman's Pavilion — Baton Rouge, Louisiana
- Oncology Hematology Associates — Springfield, Missouri
- Hematology-Oncology Associates of Central New York, P.C. (HOA) - East Syracuse - CCOP — East Syracuse, New York
- Centro de Investigaciones Médicas y Desarrollo LC — Buenos Aires, Ciudad Autónoma de Buenos Aire
- Centro De Investigaciones Medicas Mar Del Plata (CIMMDP) - Rheumatology — Mar Del Plata, Río Negro Province
- Clínica Viedma - Oncology — Viedma, Río Negro Province
- Instituto De Oncologia De Rosario — Rosario, Santa Fe Province
- ISIS Clinica Especializada — Santa Fe,
- Clinical Center University of Sarajevo - Clinic of Oncology — Sarajevo, Kanton Sarajevo
- University Clinical Center of Republic of Srpska — Banja Luka, Republika Srpska
- University Clinical Center Tuzla - Oncology, Hematology and Radio — Tuzla, Tuzlanski Kanton
- Cantonal hospital Zenica - Oncology — Zenica, Zeničko-dobojski Kanton
- Dr. Everett Chalmers Hospital - Oncology — Fredericton, New Brunswick
- Centro de Investigacion y Desarrollo Oncologico — Temuco, Araucania
- IC La Serena Research — La Serena, Coquimbo Region
- Icegclinic Research & Care — Estacion Central, Santiago Metropolitan
- Oncocentro Apys — Valparaíso, Valparaiso
- University Hospital Centre Zagreb - Oncology department — Zagreb, City of Zagreb
- Poliklinika Anova — Zagreb, City of Zagreb
- Klinicki bolnicki centar Osijek — Osijek, Osjecko-baranjska Županija
- FN Hradec Kralove - Klinika onkologie a radioterap — Hradec Kralove, Moravian-Silesian Region
- Vseobecna fakultni nemocnice v Praze - Dermatovenerologicka — Prague,
- Tartu University Hospital - Oncology — Tartu, Tartu
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Melanoma
- Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy — San Francisco, California
- An Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Participants With High-Risk Melanoma (KEYNOTE-942) — Tucson, Arizona
- Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation. — CABA, Buenos Aires
- Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients — Santa Monica, California
- NeoVax + CDX-301 and Nivolumab or Pembrolizumab in Melanoma — Boston, Massachusetts
- A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma — Orlando, Florida
Explore by condition: All Melanoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.