๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-04-29

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD (NCT06068075)

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: The LEOPARD Study

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic ๐Ÿ“‹ Clinical Research Protocol Sponsor: Dana-Farber Cancer Institute

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a prospective multicenter biomarker study evaluating the prognostic impact of ctDNA detection at diagnosis in patients with Ewing sarcoma or osteosarcoma.

Who can join: Review the eligibility criteria below.

Location: Childrens Hospital Los Angeles โ€” Los Angeles, California

Age range: 12 Months to 50 Years

๐Ÿงช Interventions in This Study

  • FoundationOne Liquid CDx (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (15 Sites)

  • Childrens Hospital Los Angeles โ€” Los Angeles, California
  • Children's Healthcare of Atlanta โ€” Atlanta, Georgia
  • Massachusetts General Hospital Cancer Center โ€” Boston, Massachusetts
  • Boston Children's Hospital โ€” Boston, Massachusetts
  • Brigham and Women's Hospital โ€” Boston, Massachusetts
  • Dana Farber Cancer Institute โ€” Boston, Massachusetts
  • Children's Hospital's and Clinics of Minnesota โ€” Minneapolis, Minnesota
  • Cincinnati Children's Hospital Medical Center โ€” Cincinnati, Ohio
  • Nationwide Children's Hospital โ€” Columbus, Ohio
  • Children's Hospital of Philadelphia โ€” Philadelphia, Pennsylvania
  • Lifespan / Rhode Island Hospital โ€” Providence, Rhode Island
  • St. Jude Children's Research Hospital โ€” Memphis, Tennessee
  • UT Southwestern Medical Center โ€” Dallas, Texas
  • University of Utah Childrens Medical Center โ€” Salt Lake City, Utah
  • Seattle Children's Hospital โ€” Seattle, Washington

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Ewing Sarcoma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—