MIRACLE of LIFE Study (NCT06074601)
Observational Study of Pregnant People to Validate Biomarkers of Pregnancy Complication Risk
🩺 Plain-English Summary (8th-Grade Level)
The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: 1. Can cell-free RNA-based biomarkers predict which pregnant people are at greatest risk of developing adverse pregnancy outcomes (e.g., preterm birth, preeclampsia)? 2. What is the performance of such biomarkers when predicting an adverse pregnancy outcome (e.g., sensitivity, specificity, PPV, NPV, TPR)?
Who can join: Review the eligibility criteria below.
Location: University of California San Diego — San Diego, California
Age range: 18 Years
🧪 Interventions in This Study
- Mirvie Predictive Test for Adverse Pregnancy Outcomes (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (10 Sites)
- University of California San Diego — San Diego, California
- Women's Care Florida — Orlando, Florida
- Ochsner Health System — New Orleans, Louisiana
- Beth Israel Deaconess Medical Center — Boston, Massachusetts
- Washington University School of Medicine — St Louis, Missouri
- The Ohio State University — Columbus, Ohio
- Thomas Jefferson University — Philadelphia, Pennsylvania
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- University of Texas Medical Branch — Galveston, Texas
- MultiCare — Tacoma, Washington
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.