🏛️ Verified NIH Record • Updated 2025-12-16

Modulation of THC Effects by CBD: a Dose-ranging Study (NCT06099379)

Modulation of ∆9-tetrahydrocannabinol Acute Psychoactive Effects by Ranging Doses of Cannabidiol in Healthy, Occasional Cannabis Users: a Controlled, Triple Blind, Randomized, Cross-over Study

🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

🩺 Plain-English Summary (8th-Grade Level)

The purposes of this study are 1) to determine if CBD modulates THC-induced acute psychoactive effects at different CBD:THC ratios, compared with the control product (0:20, 20:20, 40:20, 80:20, 120:20) and 2) to determine if different doses of CBD modulate other THC induced behavioral effects, compared with the control product and 3)To explore qualitatively whether CBD modulates THC effects by mechanisms that are not detected with standard clinical research tools.

Who can join: Review the eligibility criteria below.

Location: Centre de recherche du Centre Hospitalier Universitaire de Montréal — Montreal, Quebec

Age range: 21 Years to 49 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (1 Sites)

  • Centre de recherche du Centre Hospitalier Universitaire de Montréal — Montreal, Quebec

📞 Contact the Study Coordinator

Phone: (514) 890-8000

Email: pamela.lachance-touchette.chum@ssss.gouv.qc.ca

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Cannabis clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗