A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity (NCT06104124)
A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome With Moderate-to-severe Systemic Disease Activity
🩺 Plain-English Summary (8th-Grade Level)
Primary Objective: To evaluate the effect of dazodalibep on systemic manifestations of Sjögren's Syndrome (SS) in participants with moderate-to-severe systemic disease activity. Secondary Objectives: 1. To evaluate the effect of dazodalibep on patient reported outcomes (PROs) in participants with SS. 2. To evaluate the safety and tolerability of dazodalibep in participants with SS
Who can join: Review the eligibility criteria below.
Location: Arizona Arthritis & Rheumatology Associates - Avondale — Avondale, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (216 Sites)
Showing the first 25 of 216 sites.
- Arizona Arthritis & Rheumatology Associates - Avondale — Avondale, Arizona
- Arizona Research Clinic PLLC — Chandler, Arizona
- Arizona Arthritis and Rheumatology Associates - Flagstaff - 399 S Malpais Ln — Flagstaff, Arizona
- Arizona Arthritis and Rheumatology Associates - Gilbert - 3645 S Rome St — Gilbert, Arizona
- Arizona Arthritis and Rheumatology Associates - Glendale - 5681 W Beverly Ln — Glendale, Arizona
- Arizona Arthritis and Rheumatology Associates - Tucson - 2001 W Orange Grove Rd — Tucson, Arizona
- UCSD Altman Clinical and Translational Research Institute Building — La Jolla, California
- Inland Rheumatology Clinical Trials Incorporated — Upland, California
- Tekton Research, LLC - 2121 E Harmony Rd - PPDS — Fort Collins, Colorado
- Bradenton Research Center Inc — Bradenton, Florida
- Clinical Research of West Florida Inc - Clearwater — Clearwater, Florida
- University of Miami - Leonard M. Miller School of Medicine — Miami, Florida
- Suncoast Clinical Research - ATLAS - New Port Richey - PPDS — New Port Richey, Florida
- Millennium Research — Ormond Beach, Florida
- West Broward Rheumatology Associates, Inc. — Tamarac, Florida
- BayCare Medical Group — Tampa, Florida
- Augusta University Medical Center-Augusta-1120 15th St — Augusta, Georgia
- OrthoIllinois, LTD — Rockford, Illinois
- University of Kansas Medical Center — Kansas City, Kansas
- Massachusetts General Hospital — Boston, Massachusetts
- Clinical Research Institute of Michigan, LLC-St. Claire Shores — Saint Clair Shores, Michigan
- Kansas City Physician Partners-8350 N Saint Clair Ave — Kansas City, Missouri
- Arthritis, Rheumatic & Bone Disease Associates - P — Voorhees Township, New Jersey
- NYU Langone Health - Joseph S. and Diane H. Steinberg Ambulatory Care Center — Brooklyn, New York
- Arthritis and Osteoporosis Consultants of The Carolinas - Charlotte - 1918 Randolph Rd — Charlotte, North Carolina
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Sjogren's Syndrome
- Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome — Bethesda, Maryland
- Sjogren's Mini-Pill Oral and Gut Microbiome Study — Boston, Massachusetts
- Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease — Bethesda, Maryland
- The Pathogenesis and Natural History of Sjogren's Disease — Bethesda, Maryland
Explore by condition: All Sjogren's Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.