🏛️ Verified NIH Record • Updated 2026-06-16

Global Trial in APG2575 for Patients With CLL/SLL (NCT06104566)

A Global Multicenter, Open Label, Randomized Phase 3 Registrational Study of Lisaftoclax (APG-2575) in Previously Treated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (GLORA Study)

🟢 Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Ascentage Pharma Group Inc.

🩺 Plain-English Summary (8th-Grade Level)

This is a global multicenter, open label, randomized, registrational phase III study to investigate the efficacy and safety of lisaftoclax in combination with BTK inhibitors in CLL/SLL patients who previously treated with BTK inhibitors

Who can join: Review the eligibility criteria below.

Location: Ascentage Investigative Site — Tuscon, Arizona

Age range: 18 Years to 99 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (135 Sites)

Showing the first 25 of 135 sites.

  • Ascentage Investigative Site — Tuscon, Arizona
  • Ascentage Investigative Site — Anaheim, California
  • Ascentage Investigative Site — Jacksonville, Florida
  • Ascentage Investigative Site — Miami Beach, Florida
  • Ascentage Investigative Site — Peoria, Illinois
  • Ascentage Investigative Site — Boston, Massachusetts
  • Ascentage Investigative Site — Ann Arbor, Michigan
  • Ascentage Investigative Site — Greenville, North Carolina
  • Ascentage Investigative Site — Houston, Texas
  • Ascentage Investigative Site — Kingswood, Texas
  • Ascentage Investigative Site — Richmond, Virginia
  • Ascentage Investigative Site — Gosford,
  • Ascentage Investigative Site — Perth,
  • Ascentage Investigative Site — Westmead,
  • Ascentage Investigative Site — Ghent,
  • Ascentage Investigative Site — La Louvière,
  • Ascentage Investigative Site — Leuven,
  • Ascentage Investigative Site — Ottignies,
  • Ascentage Investigative Site — Roeselare,
  • Ascentage Investigative Site — Sofia,
  • Ascentage Investigative Site — Sofia,
  • Ascentage Investigative Site — Sofia,
  • Ascentage Investigative Site — Sofia,
  • Ascentage Investigative Site — Halifax, Nova Scotia
  • Ascentage Investigative Site — Hefei, Anhui

📞 Contact the Study Coordinator

Phone: (301) 792-5062

Email: shanthi.marur@ascentage.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All CLL/SLL clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗