AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma (NCT06106945)
A Modular Phase I/II, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0305 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Multiple Myeloma
🩺 Plain-English Summary (8th-Grade Level)
This is a Phase I/II, modular, open-label, multicenter, dose escalation, and dose expansion/optimization study to evaluate the safety, tolerability, PK, immunogenicity, pharmacodynamics and efficacy of AZD0305 as monotherapy and in combination with other anticancer agents in participants with MM.
Who can join: Review the eligibility criteria below.
Location: Research Site — Duarte, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (43 Sites)
Showing the first 25 of 43 sites.
- Research Site — Duarte, California
- Research Site — Irvine, California
- Research Site — Atlanta, Georgia
- Research Site — Boston, Massachusetts
- Research Site — Ann Arbor, Michigan
- Research Site — St Louis, Missouri
- Research Site — New York, New York
- Research Site — Philadelphia, Pennsylvania
- Research Site — Fairfax, Virginia
- Research Site — Fitzroy,
- Research Site — Melbourne,
- Research Site — Nedlands,
- Research Site — Wollongong,
- Research Site — Salvador,
- Research Site — São Paulo,
- Research Site — São Paulo,
- Research Site — Hamilton, Ontario
- Research Site — Ottawa, Ontario
- Research Site — Toronto, Ontario
- Research Site — Montreal, Quebec
- Research Site — Nova Scotia,
- Research Site — Beijing,
- Research Site — Changsha,
- Research Site — Guangzhou,
- Research Site — Shenyang,
📞 Contact the Study Coordinator
Phone: (877) 240-9479
Email: information.center@astrazeneca.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant — Tampa, Florida
- MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb — Beverly Hills, California
- A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma — Phoenix, Arizona
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Explore by condition: All Multiple Myeloma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.