Longitudinal Outpatient Treatment for Cannabis Use Disorder (NCT06107062)
Hemp-derived Cannabidiol for the Treatment of Cannabis Use Disorder: A Double-blind Placebo-controlled Randomized Trial
🩺 Plain-English Summary (8th-Grade Level)
This study is a placebo-controlled randomized trial comparing the effects of hemp-derived cannabidiol (CBD) with and without Delta-9-tetrahydrocannabinol (THC), relative to placebo, on reducing cannabis use and cannabis use disorder (CUD) symptoms in adult treatment seeking cannabis concentrate users with CUD. Participants enroll in the study for 8 weeks (with telehealth follow-ups at 12 and 16 weeks) and are randomized to either full spectrum CBD, broad spectrum CBD, or placebo. Participants are also engaged in five weeks of psychotherapy treatment for CUD. Blood is collected to quantify investigational drug exposure and cannabis use. Participants also complete self-report measures of medical history, sleep quality, subjective cognitive function, physical activity, psychological functioning, substance use, and acute drug effects.
Who can join: Review the eligibility criteria below.
Location: University of Colorado Boulder — Boulder, Colorado
Age range: 21 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Colorado Boulder — Boulder, Colorado
📞 Contact the Study Coordinator
Phone: (303) 492-9549
Email: Jonathon.Lisano@colorado.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cannabis Use Disorder
- Applying Neuromodulation to Boost the Efficacy of Motivational Interviewing — Albuquerque, New Mexico
- Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study — San Bernardino, California
- Pregnenolone for Cannabis Use Disorder and Depression — Dallas, Texas
- SV2A Density Cannabis Use Disorder — New Haven, Connecticut
- Cannabidiol and Cannabis Concentrate Users — Aurora, Colorado
- RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative — New York, New York
Explore by condition: All Cannabis Use Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.