Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis (NCT06121882)
A Randomized, Multi-center, Double Blind, Parallel Study to Examine the Effect of Lipogems Processed Microfragmented Adipose Tissue in Comparison to Saline for the Treatment of Knee Osteoarthritis
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or saline.
Who can join: Review the eligibility criteria below.
Location: Arizona Bone, Joint and Sports Medicine Center LLC — Phoenix, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- Arizona Bone, Joint and Sports Medicine Center LLC — Phoenix, Arizona
- CORE Orthopaedic Medical Center — Encinitas, California
- Horizon Clinical Research — La Mesa, California
- Andrews Research & Ed Foundation — Gulf Breeze, Florida
- Hospital for Special Surgery Florida — West Palm Beach, Florida
- Pinnacle Trials, Inc — Atlanta, Georgia
- Fascia Institute and Treatment (FIT) Center — Metairie, Louisiana
- Ochsner Sports Medicine Institute — New Orleans, Louisiana
- Regenerative Orthopedics & Sports Medicine — Rockville, Maryland
- Mayo Clinic - Rochester — Rochester, Minnesota
- The Orthopedic Center - NextStage Clinical Research - Tulsa — Tulsa, Oklahoma
- LeHigh Center for Clinical Research — Allentown, Pennsylvania
- Coastal Carolina Research Center — North Charleston, South Carolina
- Vanderbilt Orthopaedics — Nashville, Tennessee
- All American Ortho - NextStage Clinical Research — Houston, Texas
- Texas Center for Cell Therapy and Research, LLC — San Antonio, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Knee Osteoarthritis
- A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis — Tucson, Arizona
- Dronabinol After Arthroscopic Surgery — Chicago, Illinois
- Telehealth Stepped Exercise Program for Rural Veterans With Knee Osteoarthritis — Durham, North Carolina
- Early Outcomes of MAKO Medial Unicompartmental Knee Arthroplasty — St Louis, Missouri
- GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA (MOTION) — Long Beach, California
Explore by condition: All Knee Osteoarthritis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.