Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy (NCT06138873)
Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy (AIM-VT) - a Prospective Single-Blinded, Multicenter Randomized Controlled Trial
🩺 Plain-English Summary (8th-Grade Level)
Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in real time and ensuring an effective transmural lesion, different surrogate measures of lesion quality have been used. The Ablation Index (AI) is a variable incorporating power delivery in its formula and combining it with CF and time in a weighted equation which aims at allowing for a more precise estimation of lesion depth and quality when ablating VAs. AI guidance has previously been shown to improve outcomes in atrial and ventricular ablation in patients with premature ventricular complexes (PVC). However research on outcomes following AI-guidance for VT ablation specifically in patients with structural disease and prior myocardial infarction remains sparse. The investigators aim at conducting the first randomized controlled trial testing for the superiority of an AI-guided approach regarding procedural duration.
Who can join: Review the eligibility criteria below.
Location: Rush University Medical Center — Chicago, Illinois
Age range: 18 Years
🧪 Interventions in This Study
- Ablation-index guided ventricular tachycardia ablation (PROCEDURE)
- Ventricular tachycardia ablation with no AI-guidance (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- Rush University Medical Center — Chicago, Illinois
- Mass General Brigham and Women's Hospital — Boston, Massachusetts
- Medical University of Michigan — Ann Arbor, Michigan
- Mayo Clinic — Rochester, Minnesota
- Medical University of South Carolina — Charleston, South Carolina
📞 Contact the Study Coordinator
Phone: (312) 942-5020
Email: alexander_mazur@rush.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ventricular Tachycardia
- Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) — Chandler, Arizona
- Abbott Ventricular Tachycardia PAS — Naples, Florida
- Cardiac Radioablation for VT — Royal Oak, Michigan
- Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial — Ottawa, Ontario
- Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm — Rochester, Minnesota
- Trial in Arrhythmia Radioablation for Ventricular Tachycardia: Single Fraction vs Three Fractions — New York, New York
Explore by condition: All Ventricular Tachycardia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.