๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-27

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide (NCT06208150)

64407564MMY3009: A Phase 3 Randomized Study Comparing Talquetamab in Combination With Pomalidomide (Tal-P), Talquetamab in Combination With Teclistamab (Tal-Tec), and Investigator's Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pom

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to compare the effectiveness of either talquetamab plus pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone (PVd).

Who can join: Review the eligibility criteria below.

Location: UCSF Fresno โ€” Clovis, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (242 Sites)

Showing the first 25 of 242 sites.

  • UCSF Fresno โ€” Clovis, California
  • UCLA โ€” Santa Monica, California
  • Yale University School Of Medicine โ€” New Haven, Connecticut
  • Medical Oncology Hematology Consultants, PA โ€” Newark, Delaware
  • Memorial Healthcare System โ€” Hollywood, Florida
  • Moffitt Cancer Center โ€” Tampa, Florida
  • Winship Cancer Institute Emory University โ€” Atlanta, Georgia
  • City of Hope Cancer Center โ€” Newnan, Georgia
  • Kootenai Health โ€” Coeur d'Alene, Idaho
  • Loyola University Medical Center โ€” Maywood, Illinois
  • University of Iowa Health Care โ€” Waukee, Iowa
  • Norton Cancer Institute โ€” Louisville, Kentucky
  • Our Lady of the Lake Hospital โ€” Baton Rouge, Louisiana
  • Luminis Health Center for Cancer and Blood Disorders โ€” Annapolis, Maryland
  • University of Maryland School of Medicine โ€” Baltimore, Maryland
  • The Sidney Kimmel Comprehensive Cancer Center at John Hopkins โ€” Baltimore, Maryland
  • University of Michigan โ€” Ann Arbor, Michigan
  • Henry Ford Cancer Institute โ€” Detroit, Michigan
  • Henry Ford Health Providence Southfield Hospital โ€” Southfield, Michigan
  • University Of Minnesota โ€” Minneapolis, Minnesota
  • Mayo Clinic Rochester โ€” Rochester, Minnesota
  • Regions Hospital โ€” Saint Paul, Minnesota
  • University of Nebraska โ€” Omaha, Nebraska
  • Dartmouth Hitchcock Medical Center โ€” Lebanon, New Hampshire
  • John Theurer Cancer Center at Hackensack University Medical Center โ€” Hackensack, New Jersey

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 827-3222

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—