TRAIL Study: Feasibility and Pilot (NCT06220656)
ThyRoid Active Monitoring and Intervention Longitudinal (TRAIL) Study: Feasibility and Pilot
🩺 Plain-English Summary (8th-Grade Level)
This is a pilot study to compare two ways of managing newly identified thyroid nodules that are likely to be cancerous based on ultrasound result and which under usual care would undergo immediate biopsy. The main goals of this pilot study are 1) compare anxiety at 6 months in each treatment arm using the validated instrument Anxiety-CA, 2) measure thyroid quality of life in each treatment arm Participants will be randomized to one of two groups: 1. immediate biopsy (usual care) 2. Active monitoring (serial ultrasound based monitoring and close clinical follow-up)
Who can join: Review the eligibility criteria below.
Location: Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire
Age range: 18 Years
🧪 Interventions in This Study
- Biopsy (PROCEDURE)
- Active Monitoring (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire
📞 Contact the Study Coordinator
Phone: (603) 305-3529
Email: michaela.m.geffert@hitchcock.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Thyroid Nodule
- Active Surveillance Program in Thyroid Nodules — Medellín, Antioquia
- Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System — Sarasota, Florida
- Decision Aid and Thyroid Nodules Management — Stony Brook, New York
- The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer — Toronto, Ontario
- Radiofrequency Ablation Study in LatinX Patients — New York, New York
Explore by condition: All Thyroid Nodule clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.