🏛️ Verified NIH Record • Updated 2025-11-18

An Extension Study to Evaluate the Long-Term Safety and Efficacy of Votoplam in Participants With Huntington's Disease (HD) (NCT06254482)

A Phase 2b, Double-Blind, Randomized Extension Study to Evaluate the Long-Term Safety and Efficacy of Votoplam in Participants With Huntington's Disease

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals

🩺 Plain-English Summary (8th-Grade Level)

The primary goal of this study is to evaluate the long-term safety and pharmacodynamic effects of votoplam in participants with HD.

Who can join: Review the eligibility criteria below.

Location: Novartis Investigative Site — Clayton

Age range: 25 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (24 Sites)

  • Novartis Investigative Site — Clayton,
  • Novartis Investigative Site — Westmead,
  • Novartis Investigative Site — Innsbruck,
  • Novartis Investigative Site — Ottawa,
  • Novartis Investigative Site — Angers,
  • Novartis Investigative Site — Marseille,
  • Novartis Investigative Site — Paris,
  • Novartis Investigative Site — Berlin,
  • Novartis Investigative Site — Bochum,
  • Novartis Investigative Site — Münster,
  • Novartis Investigative Site — Ulm,
  • Novartis Investigative Site — Bologna,
  • Novartis Investigative Site — Milan,
  • Novartis Investigative Site — San Giovanni Rotondo,
  • Novartis Investigative Site — Leiden,
  • Novartis Investigative Site — Christchurch,
  • Novartis Investigative Site — Barakaldo,
  • Novartis Investigative Site — Barcelona,
  • Novartis Investigative Site — Burgos,
  • Novartis Investigative Site — Madrid,
  • Novartis Investigative Site — Birmingham,
  • Novartis Investigative Site — Cardiff,
  • Novartis Investigative Site — London,
  • Novartis Investigative Site — Manchester,

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗