๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-14

First In Human Study of CX-2051 in Advanced Solid Tumors (NCT06265688)

An Investigational Study of CX-2051 in Participants With Advanced Solid Tumors

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: CytomX Therapeutics

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this first-in-human study, CTMX-2051-101, is to characterize the safety, tolerability, and antitumor activity of CX-2051 as a monotherapy and in combination with bevacizumab in adult participants with advanced solid tumors.

Who can join: Review the eligibility criteria below.

Location: Sarah Cannon Research Institute at HealthONE โ€” Denver, Colorado

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (8 Sites)

  • Sarah Cannon Research Institute at HealthONE โ€” Denver, Colorado
  • Dana-Farber Cancer Institute โ€” Boston, Massachusetts
  • Montefiore Medical Center โ€” The Bronx, New York
  • Carolina BioOncology Institute, PLLC โ€” Huntersville, North Carolina
  • Sarah Cannon Research Institute, LLC โ€” Nashville, Tennessee
  • START - Dallas/Fort Worth โ€” Fort Worth, Texas
  • START San Antonio LLC โ€” San Antonio, Texas
  • NEXT Virginia โ€” Fairfax, Virginia

๐Ÿ“ž Contact the Study Coordinator

Phone: (650) 515-3185

Email: clinicaltrials@cytomx.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—