Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease (NCT06268886)
A Randomized, Double-blind, Placebo-controlled, Global Proof-of-concept Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986446, an Anti-MTBR Tau Monoclonal Antibody, in Participants With Early Alzheimer's Disease (TargetTau-1)
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants with Early Alzheimer's Disease.
Who can join: Review the eligibility criteria below.
Location: Local Institution - 0068 โ Chandler, Arizona
Age range: 50 Years to 80 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (176 Sites)
Showing the first 25 of 176 sites.
- Local Institution - 0068 โ Chandler, Arizona
- Local Institution - 0102 โ Gilbert, Arizona
- Local Institution - 0019 โ Phoenix, Arizona
- Local Institution - 0018 โ Scottsdale, Arizona
- Local Institution - 0026 โ Scottsdale, Arizona
- Local Institution - 0077 โ Tucson, Arizona
- Local Institution - 0038 โ Tucson, Arizona
- Local Institution - 0164 โ Encino, California
- Local Institution - 0139 โ Fullerton, California
- Local Institution - 0191 โ Irvine, California
- Local Institution - 0234 โ Long Beach, California
- Local Institution - 0142 โ Los Alamitos, California
- Local Institution - 0037 โ Napa, California
- Local Institution - 0209 โ Sacramento, California
- Local Institution - 0052 โ San Francisco, California
- Local Institution - 0137 โ Santa Ana, California
- Local Institution - 0046 โ Sherman Oaks, California
- Local Institution - 0106 โ Danbury, Connecticut
- Local Institution - 0148 โ New Haven, Connecticut
- Local Institution - 0056 โ New Haven, Connecticut
- Local Institution - 0153 โ Stamford, Connecticut
- Local Institution - 0022 โ Altamonte Springs, Florida
- Local Institution - 0048 โ Atlantis, Florida
- Local Institution - 0228 โ Boca Raton, Florida
- Local Institution - 0250 โ Boca Raton, Florida
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Alzheimer Disease, Early Onset
- Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study โ Winston-Salem, North Carolina
- Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease โ Baltimore, Maryland
- PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD) โ Irvine, California
- Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau โ New York, New York
- Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD โ Los Angeles, California
Explore by condition: All Alzheimer Disease, Early Onset clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.