The Tryptophan Requirement in Healthy Adults (NCT06283706)
The Tryptophan Requirement in Healthy Adults Over 60 Years
🩺 Plain-English Summary (8th-Grade Level)
The aging population is growing rapidly. For the first time ever, Canadian seniors outnumbered young adults in 2016. Aging is associated with many physical and metabolic deteriorations including the loss of muscle mass and strength, insulin resistance, increased inflammation and oxidative stress. The muscles of our bodies are composed of proteins and proteins are made of small building blocks called amino acids. Our bodies have the ability to make some amino acids which are called the non-essential amino acids. However, there are certain amino acids that our body's need to make protein but can only be supplied from the foods that we consume. These are called essential amino acids. Tryptophan is one of the essential amino acids that the body needs. Tryptophan is required for protein synthesis and acts as a precursor for serotonin and nicotinic acid. Therefore, there may be a need for more threonine in the diet of older adults. However, the current requirement for threonine is based on studies conducted exclusively in young adults. Thus, the purpose of this study is to find out how much tryptophan older adults need.
Who can join: Review the eligibility criteria below.
Location: Hospital for Sick Children — Toronto, Ontario
Age range: 60 Years to 90 Years
🧪 Interventions in This Study
- Tryptophan (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Hospital for Sick Children — Toronto, Ontario
📞 Contact the Study Coordinator
Phone: (437) 419-6224
Email: zhiyao.wang@sickkids.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Healthy Aging
- Piloting a Healthy Aging Cohort in Manitoba — Winnipeg, Manitoba
- Protein-Distinct Macronutrient-Equivalent Diet 2 — Brookings, South Dakota
- An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial — Hazard, Kentucky
- The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health — Tampa, Florida
- Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults — New London, New Hampshire
- Multivitamin and Mineral Supplementation and Healthy Aging — La Jolla, California
Explore by condition: All Healthy Aging clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.