Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium (NCT06284213)
🩺 Plain-English Summary (8th-Grade Level)
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID) is an NIH-funded consortium dedicated to finding biomarkers involved in age-related thinking and memory problems. Alzheimer's disease and other dementias leave signatures on brain scans or in the blood called biomarkers. The MarkVCID study will measure a panel of candidate biomarkers in 1800 participants and watch them closely to see what they tell us about changes in brain function and risk of memory loss. Age-related problems in thinking and memory represent some of the greatest risks to public health in the US and globally. Diseases that affect small blood vessels in the brain have been shown to be major contributors to these changes. However, research and patient care can be held back by limited biomarkers that identify who should be treated. The MarkVCID Consortium includes 17 US medical centers, a Coordinating Center, an External Advisory Committee, and NIH leadership. Data and biospecimens collected as part of this research study will be stored in a research database and biorepositories, so that researchers can use this information to study brain function.
Who can join: Review the eligibility criteria below.
Location: University of Southern California — Los Angeles, California
Age range: 60 Years to 90 Years
🧪 Interventions in This Study
- No interventions (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (17 Sites)
- University of Southern California — Los Angeles, California
- University of California Los Angeles — Los Angeles, California
- University of California Davis — Sacramento, California
- University of California San Francisco — San Francisco, California
- Olive View - UCLA Medical Center — Sylmar, California
- Mayo Clinic Florida — Jacksonville, Florida
- Rush University Medical Center & Illinois Institute of Technology — Chicago, Illinois
- University of Kentucky — Lexington, Kentucky
- University of Maryland, Baltimore — Baltimore, Maryland
- Johns Hopkins University — Baltimore, Maryland
- Mayo Clinic Rochester — Rochester, Minnesota
- University of Mississippi Medical Center — Jackson, Mississippi
- Washington University in St. Louis — St Louis, Missouri
- University of New Mexico — Albuquerque, New Mexico
- University of Texas Southwestern — Dallas, Texas
- University of Texas Health Science Center Houston — Houston, Texas
- University of Texas Health Science Center San Antonio — San Antonio, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Cognitive Impairment clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.