Massed Prolonged Exposure for PTSD in Substance Use Treatment (NCT06296186)
Clinical Effectiveness and Implementation of Massed Prolonged Exposure for PTSD Among Veterans in Intensive Outpatient Substance Use Treatment (MPE)
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are: * Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms? * Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.
Who can join: Review the eligibility criteria below.
Location: VA San Diego Healthcare System — San Diego, California
Age range: 18 Years
🧪 Interventions in This Study
- Prolonged Exposure Therapy (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- VA San Diego Healthcare System — San Diego, California
- VA Tampa Healthcare System — Tampa, Florida
- VA Atlanta Healthcare System — Atlanta, Georgia
- Hines VA Healthcare System — Chicago, Illinois
- New Orleans VA Medical Center — New Orleans, Louisiana
- Cleveland VA — Cleveland, Ohio
📞 Contact the Study Coordinator
Phone: (858) 518-8266
Email: snorman@ucsd.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.