Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure (NCT06296589)
Clinical Effectiveness and Implementation of Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure (TrIGR)
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt. The main questions it aims to answer are: Will TrIGR be comparable to PE in terms of PTSD symptom reduction? Will it TrIGR be comparable to PE in improving functioning and reducing depression symptoms? Will it be superior in improving trauma-related guilt and shame?
Who can join: Review the eligibility criteria below.
Location: Little Rock Veterans Health Care System (LRVHCS) — Little Rock, Arkansas
Age range: 18 Years
🧪 Interventions in This Study
- Trauma Informed Guilt Reduction Therapy (BEHAVIORAL)
- Prolonged Exposure Therapy (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- Little Rock Veterans Health Care System (LRVHCS) — Little Rock, Arkansas
- VA San Diego — San Diego, California
- Southeast Louisiana Veterans Health Care System (SLVHCS) — New Orleans, Louisiana
- William S. Middleton Memorial Hospital — Madison, Wisconsin
📞 Contact the Study Coordinator
Phone: (858) 518-8266
Email: snorman@ucsd.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.